Iran's Revolutionary Guards said Wednesday they had "complete control" of the crucial Strait of Hormuz and Israel launched new strikes on Iranian and Lebanese targets as the Middle East war continued into its fifth day.
Here are the latest developments:
Iran has no intention of negotiating with the United States and can continue the war for "as long as we want", Mohammad Mokhber, a senior aide to late supreme leader Ayatollah Ali Khamenei, told state TV.
The country's judiciary chief meanwhile warned anyone aiding Iran's enemies would "be dealt with decisively and severely", after the United States and Israel called on Iranians to rise up against the Islamic republic's authorities.
The Israeli military said it had begun a fresh wave of strikes on Tehran on Wednesday, as an AFP journalist reported a fresh explosion in the northeast of the Iranian capital.
The army said it had struck "dozens" of targets, including security command centres in Tehran, and had shot down an Iranian fighter jet over the capital.
Sri Lanka said an Iranian navy frigate with 180 crew sank just outside the island's territorial waters after an explosion.
No information was immediately available on the cause.
The Sri Lankan foreign minister said 32 "critically wounded" sailors had been rescued from the warship, the IRIS Dena, after it issued a distress call at dawn. A search for remaining crew was ongoing.
France said it was planning a meeting of G7 finance ministers on the crisis for early next week, with central bankers also in attendance.
Spanish Prime Minister Pedro Sanchez hit back at President Donald Trump's criticisms of Madrid's refusal to let US planes use its bases to attack Iran.
"No to war," he said in a televised address, a day after Trump threatened to sever all trade with Spain.
An EU spokesman said the bloc was "ready to act" to safeguard the bloc's interests.
Canadian Prime Minister Mark Carney said Wednesday that US-Israeli strikes on Iran had been "inconsistent with international law", calling for a rapid de-escalation of the conflict.
Speaking at a gathering of the Lowy Institute think tank in Sydney, Carney said Canada welcomed steps to change Iran's form of government -- which he said represented the "principal source of instability and terror" in the Middle East.
But, he said, the action "would appear, prima facie, not to be consistent or to be inconsistent with international law".
"It's a judgement for others to make," he added. "I'm not a lawyer, let alone an international legal expert."
The Revolutionary Guards said Iranian forces had "complete control" of the Strait of Hormuz, a vital route for world oil and gas supplies, and any vessels seeking to pass risked damage from missiles or stray drones.
US President Donald Trump said Tuesday the US Navy was ready to escort oil tankers through the crucial Gulf shipping route.
The Guards said they had also launched more than 40 missiles at US and Israeli targets in a new wave of strikes.
Iran will hold a three-day-long state funeral starting on Wednesday evening for Ayatollah Ali Khamenei, state TV said.
Khamenei, the Islamic Republic's supreme leader, was killed in the US-Israeli strikes that sparked the war on Saturday.
After the funeral's announcement, Israel's defence minister warned that any successor would be a "target for assassination".
The Dubai and Abu Dhabi stock exchanges reopened sharply lower on Wednesday after a two-day trading suspension over Iran's missile and drone attacks across the Gulf.
The Dubai bourse was down 4.7 percent while Abu Dhabi's ADX fell 3.5 percent shortly after markets opened.
Seoul shares earlier collapsed more than 12 percent as Asian stock markets were gripped by the worldwide wave of panic selling. Oil rose.
Missiles launched from Iran early Wednesday triggered air raid sirens across large parts of Israel, including Jerusalem and Tel Aviv.
The military said it was "operating to intercept the threat", and the alert was lifted after several minutes with no immediate reports of casualties -- though shrapnel caused a fire near Jerusalem, according to Israeli media.
Sri Lanka said an Iranian navy frigate with 180 crew was sinking just outside the island's territorial waters.
No information was immediately available on the cause.
AFPTV footage showed an air strike hit Hezbollah's bastion in the southern suburbs of the Lebanese capital Beirut, as Israel and the Iran-backed militant group traded strikes and rocket fire.
Lebanon's health ministry said Israeli strikes on two towns south of Beirut -- outside of Iran-backed Hezbollah's traditional strongholds -- killed six people and wounded eight.
Lebanese state media later said Israeli strikes had hit a hotel in the Beirut suburb of Hazmieh, as well as a four-storey building in the eastern city of Baalbek, where five people were reportedly killed.
Admiral Brad Cooper, who leads US military forces in the Middle East, said in a video message that nearly 2,000 targets had been struck so far in Iran.
"We have severely degraded Iran's air defences and destroyed hundreds of Iran's ballistic missiles, launchers and drones," he said.
The Saudi defence ministry said two cruise missiles were intercepted over an area south of the capital Riyadh, and state media reported nine drones targeting the kingdom were intercepted.
A drone was also shot down near the international airport in the Iraqi capital Baghdad, a security source said.
Qatar, which hosts a major US military base and has been targeted by multiple Iranian strikes since the outbreak of the war, reported it had dismantled two spy cells linked to the Revolutionary Guards, arresting 10 suspects.
Israel's military said Wednesday it has launched a "broad wave of strikes" on Iran, after the Islamic republic launched three separate missile barrages at Israeli territory.
The army said it had struck "dozens" of targets, including security command centres in the capital Tehran.
A drone attack caused a fire by the US consulate in Dubai as Iran ramped up its targeting of American diplomatic missions in the Gulf.
The United States said it had ordered non-emergency staff at its consulates in the Pakistani cities of Lahore and Karachi to leave the country over "safety risks", and granted permission for staff to leave missions in Saudi Arabia, Cyprus and Oman.